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Corbin Carroll and the Arizona Diamondbacks will hit the field on Wednesday at Chase Field against Nestor Cortes, who starts for the San Diego Padres. First pitch will be at 9:40 p.m. ET for the second game of a three-game series. Bookmakers list the Padres as -145 favorites on the moneyline, while giving the underdog Diamondbacks +121 moneyline odds to win. San Diego is favored on the run line (-1.5 with +110 odds). The over/under for the matchup has been listed at 9.5 runs.
Check out everything you need to know from a betting perspective on the Padres-Diamondbacks game, regarding the run line, moneyline and total, plus expert picks.
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Padres vs. Diamondbacks Highlights | MLB on FOX
Check out the best moments from this MLB matchup between the San Diego Padres and the Arizona Diamondbacks.
Padres vs. Diamondbacks Game Information & Odds
- When: Wednesday, August 6, 2025 at 9:40 p.m. ET
- Where: Chase Field in Phoenix, Arizona
- How to watch on TV: MLB Network, ARID, and SDPA
| Favorite | Favorite Moneyline | Underdog Moneyline | Total | Over Total Odds | Under Total Odds | Run Line | Favorite Run Line Odds | Underdog Run Line Odds |
|---|---|---|---|---|---|---|---|---|
| Parents | -145 | +121 | 9.5 | -102 | -119 | -1.5 | +110 | -132 |
Padres vs. Diamondbacks Prediction
- Score Prediction: Diamondbacks 5, Padres 4
- Total Prediction: Under 9.5 runs
- Win Probabilities: Padres 51%, Diamondbacks 49%
Padres vs. Diamondbacks Betting Insights
- The Padres have entered the game as favorites 60 times this season and won 35, or 58.3%, of those games.
- San Diego has a record of 20-14, a 58.8% win rate, when favored by -145 or more by sportsbooks this season.
- The moneyline for this contest implies a 59.2% chance of a victory for the Padres.
- The Diamondbacks have been victorious in 20, or 45.5%, of the 44 contests they have been chosen as underdogs in this season.
- This season, Arizona has been victorious 11 times in 16 chances when named as an underdog of at least +121 or longer on the moneyline.
- The Diamondbacks have an implied victory probability of 45.2% according to the moneyline set for this matchup.
Padres Recent Betting Performance
- The Padres have a 4-3 record across the seven games they were favored on the moneyline in their last 10 matchups.
- In their last 10 matchups — all had a set run total — the Padres and their opponents combined to hit the over on the total four times.
- The Padres have gone 6-4-0 against the spread over their past 10 games.
Padres Recent Stats
| Stat | Avg/Total |
|---|---|
| Record | 7-3 |
| Runs Per Game | 4.9 |
| HR | 7 |
| ERA | 3.07 |
| K/9 | 8.5 |
Padres Player Insights
- Manny Machado has racked up a team-high batting average of .299, while leading the Padres in home runs (20) and runs batted in (72).
- Among all MLB hitters, Machado is ninth in batting average, 32nd in on-base percentage, and 20th in slugging.
- Fernando Tatis Jr. has 19 doubles, two triples, 17 home runs and 64 walks while batting .264.
- Tatis ranks 57th in homers and 114th in RBI among all major league hitters this season.
- Tatis has two games in a row with at least one hit. During his last five outings he is batting .167 with a double and five walks.
- Luis Arraez is batting .296 with 21 doubles, four triples, six home runs and 23 walks.
- Xander Bogaerts has 24 doubles, seven home runs and 44 walks while batting .267.
Diamondbacks Recent Betting Performance
- The Diamondbacks have played as underdogs in eight of their past 10 games and won three of those contests.
- In their last 10 games with a total, the Diamondbacks and their opponents have combined to hit the over just once.
- The Diamondbacks have won three of their last 10 games against the spread.
Diamondbacks Recent Stats
| Stat | Avg/Total |
|---|---|
| Record | 4-6 |
| Runs Per Game | 2.6 |
| HR | 8 |
| ERA | 4.29 |
| K/9 | 6.6 |
Diamondbacks Player Insights
- Geraldo Perdomo has sent home a team-high 75 runs batted in.
- Perdomo’s home run total places him 126th in the majors, and he ranks 11th in RBI.
- Carroll’s 22 home runs are a team-high total.
- Carroll is 20th overall in homers and 61st in RBI this year.
- Ketel Marte leads the Diamondbacks with a team-best batting average of .291.
- Lourdes Gurriel Jr. has 21 doubles, two triples, 12 home runs and 26 walks while batting .247.
Padres vs. Diamondbacks Highlights | MLB on FOX
Check out the best moments from this MLB matchup between the San Diego Padres and the Arizona Diamondbacks.
FOX Sports created this story using technology provided by Data and data from Sportradar.
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